All-cause and cause-specific mortality in patients with depression in Scotland

Introduction Premature mortality in people with depression is well established. A better understanding of the causes death and relative risks from each cause may help identify factors that contribute to health inequalities between without depression. Objectives To describe all-cause cause-specific a hospital admission record for Scotland, general population. Methods We used linked population-based dataset all psychiatric admissions Scotland national 28,837 adults ≥18 years age who had 2000 2019. obtained population estimates data National Records quantified difference by calculating standardised ratio (SMR), using indirect standardisation stratifying sex. Results During median follow-up 8.1 years, 7,931(27.5%) were hospitalised died. Circulatory system diseases most common death. Standardised was more than three times higher would be expected based on rates Scottish SMRs similar men women and, general, (Table 1). The SMR suicide category markedly men, partly explained males females Table 1 All-cause 2000-19 Observed deaths, n (All) Expected (95% CI) (Male) (Female) (Female 7,931 2427 3.3(3.2-3.3) 3617 1052 3.4(3.3-3.5) 4314 1375 3.1(3.0-3.2) 2,020 806 2.5(2.4-2.6) 886 343 2.6(2.4-2.7) 1,134 463 2.4(2.3-2.6) Neoplasms 1,153 682 1.7(1.6-1.8) 534 306 1.7(1.6-1.9) 619 376 1.6(1.5-1.8) Respiratory 1,106 292 3.8(3.6-4.0) 453 112 4.0(3.7-4.4) 653 180 3.6(3.3-3.9) Mental & behavioural disorders 835 131 6.4(5.9-6.8) 333 52 6.4(5.7-7.2) 502 79 6.3(5.8-6.9) Accidents 395 69 5.7(5.2-6.3) 224 38 5.9(5.1-6.7) 171 31 5.5(4.7-6.3) Suicide, self-harm injuries undetermined Intent 805 53 15.2(14.1-16.2) 485 39 12.4(11.3-13.5) 320 14 22.9(20.3-25.4) Other external 28 6 4.7(2.9-6.4) 16 3 5.3 (2.7- 7.9) 12 4.0(1.7-6.3) natural 1,589 388 4.1(3.9-4.3) 686 159 4.3 (4.0-4.6) 903 229 3.9(3.7-4.2) CI: Confidence interval; SMR: Conclusions People continue have varying Disclosure Interest None Declared